We are in constant pursuit of breakthroughs that transform patients' lives. We innovate each day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies deliver better results, are more inventive, draw and keep the best professionals, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—drives everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and reflects the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We embody our purpose by seeking the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.