We are in tireless pursuit of breakthroughs that transform patients' lives. We innovate daily to make the world a healthier place. It was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what we instinctively know: that purpose-driven companies deliver better results, are more inventive, draw and keep the best talent, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and embodies the value we aim to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.