We are in relentless pursuit of breakthroughs that transform patients' lives. We drive innovation daily to make the world a better place. This was Charles Pfizer's original vision, and it holds true today. Evidence confirms what we instinctively know: that purpose-driven companies achieve more, are more inventive, draw and keep the best professionals, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and demonstrates our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We fulfill our purpose by seeking the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.