We are in constant pursuit of breakthroughs that transform patients' lives. We drive innovation daily to make the world a better place. This was Charles Pfizer's initial vision, and it still holds true today. Studies show what intuition tells us: that purpose-driven companies deliver better results, are more inventive, attract and retain the best professionals, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and reflects our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and embodies the value we strive to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to push for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.