We are in relentless pursuit of breakthroughs that transform patients' lives. We innovate daily to make the world a healthier place. This was Charles Pfizer's original vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, attract and retain the best people, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and embodies the value we strive to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We fulfill our purpose by finding the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every decision we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.