We are in constant pursuit of breakthroughs that change patients' lives. We create innovations daily to make the world a better place. This was Charles Pfizer's original vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best talent, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and shows our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we aim to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We live our purpose by seeking the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can prosper.